Differentiation of Prions from L-type BSE versus Sporadic Creutzfeldt-Jakob Disease

نویسندگان

  • Simon Nicot
  • Anna Bencsik
  • Eric Morignat
  • Nadine Mestre-Francés
  • Armand Perret-Liaudet
  • Thierry Baron
چکیده

We compared transmission characteristics for prions from L-type bovine spongiform encephalopathy and MM2-cortical sporadic Creutzfeldt-Jakob disease in the Syrian golden hamster and an ovine prion protein-transgenic mouse line and isolated distinct prion strains. Our findings suggest the absence of a causal relationship between these diseases, but further investigation is warranted.

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عنوان ژورنال:

دوره 18  شماره 

صفحات  -

تاریخ انتشار 2012